Review Article
Ribavirin at the Era of Novel Direct Antiviral Agents for the Treatment of Hepatitis C Virus Infection: Relevance of Pharmacological Monitoring
Table 4
Mean ribavirin plasma concentration.
| Patients () | Dialysis patients ( | Moderate or severe renal insufficiency () | Treatment response | Responder | Nonresponder | Responder | Nonresponder |
| W4 | | | | | EVR | 1.47 | 0.91 | 2.7 | 2.36 | SVR | 1.26 (RR: 0.56) | 2.86 (RR: 2.54) | W8 | | | | | EVR | 1.48 | 1.22 | 2.5 | 2.15 | SVR | 1.38 (RR: 0.8) | 2.76 (RR: 2.31) | W12 | | | | | EVR | 1.65 | 1.42 | 2.79 | 3.07 | SVR | 1.74 (RR: 1.48) | 3.22 (RR: 2.43) |
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