Targeting Hepatic Glycerolipid Synthesis and Turnover to Treat Fatty Liver Disease

Figure 1

The pathways for triglyceride synthesis and hydrolysis are shown. Fatty acid (FA), phosphate (P), glycerol-3-phosphate (G-3-P), G-3-P acyltransferase (GPAT), lysophosphatidic acid (LPA), acylglycerol-3-phosphate acyltransferase (AGPAT), phosphatidic acid (PA), monoacylglycerol (MAG), MAG acyltransferase (MGAT), diacylglycerol (DAG), DAG acyltransferase (DGAT), triglyceride (TG), lipid droplet (LD), LD protein (LDP), adipose tissue triglyceride lipase (ATGL), hormone sensitive lipase (HSL), MAG lipase (MAGL), and endoplasmic reticulum (ER).