Cholangiocarcinomas: New Insights from the Discovery of Stem Cell Niches in Peribiliary Glands of the Biliary Tree
Figure 2
Biliopancreatic stem/progenitors in peribiliary glands of adult liver. The immunofluorescence demonstrated stem cells deeper inside of the wall, co-expressing endodermal nuclear transcription factors essential for liver and pancreas formation (e.g., PDX1 in red) together with endodermal stem cell markers (e.g., EpCAM in green) (arrows).