Research Article
An Association between Single Nucleotide Polymorphisms of Lys751Gln ERCC2 Gene and Ovarian Cancer in Polish Women
Table 1
Characteristics of the study population (
).
| | Characteristics | Number of cases (%) |
| | Histology of tumour | | | Serous | 148 (34.4) | | Mucinous | 20 (4.7) | | Endometrioid | 120 (27.9) | | Clear cell | 23 (5.3) | | Undifferentiated | 103 (24.0) | | Other | 16 (3.7) |
| | Number of pregnancies | | | 1 | 196 (46) | | 2-3 | 152 (35) | | 4 | 82 (19) |
| | Body mass index | | | 19 0 0 | 34 (8.0) | | 18–25 25 37 | 260 (60.4) | | 26–29 40 50 | 98 (22.8) | | 30 | 38 (8.8) |
| | Smoking status | | | Never | 99 (23) | | Ever | 172 (40) | | Moderate | 60 (14) | | Heavy | 99 (23) |
| | Alcohol intake | | | Never/rare | 132 (31) | | Light | 108 (25) | | Moderate | 60 (14) | | Heavy | 64 (15) | | Ex-drinker | 66 (15) |
| | Family history of ovarian cancer | | | Yes | 150 (35) | | No | 280 (65) |
| | Ascites | | | Present | 153 (36) | | Absent | 277 (64) |
| | Use of hormone replacement therapy (HRT) | | | Yes | 293 (8) | | No | 137 (32) |
| | Size of tumor | | | 5 cm | 270 (63) | | 5 cm | 160 (37) |
| | Tumour wall infiltration/injury | | | Present | 129 (30) | | Absent | 301 (70) |
| | Menarche | | | 12 years old | 290 (67) | | 12 years old | 140 (33) |
| | Grading | | | G1 | 200 (47) | | G2 | 220 (51) | | G3 | 10 (2) |
| | Staging | | | I | 190 (44) | | II | 230 (54) | | III | 10 (2) |
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