An Association between Single Nucleotide Polymorphisms of Lys751Gln ERCC2 Gene and Ovarian Cancer in Polish Women

Table 3

Dependence of ERCC2 gene polymorphism genotypes and allele frequency on tumour grade in patients with ovarian cancer.

Grade	Ovarian cancer patients
	G1 ()	G2 + G3 ()	OR (95% CI)
ERCC2-Lys751Gln	Number (%)	Number (%)
Lys/Lys	10 (5%)	52 (22.6%)	1.00 Ref.
Lys/Gln	16 (8%)	48 (20.9%)	1.73 (0.71–4.18)	0.312
Gln/Gln	174 (87%)	130 (56.5%)	6.96 (3.41–14.21)	<0.0001
Lys	36 (9%)	152 (33%)	1.00 Ref.
Gln	364 (91%)	308 (67%)	4.98 (3.37–7.40)	<0.0001

; according to FIGO criteria; crude odds ratio (OR); 95% CI: confidence interval at 95%; Chi square.