Research Article
An Association between Single Nucleotide Polymorphisms of Lys751Gln ERCC2 Gene and Ovarian Cancer in Polish Women
Table 4
Dependence of genotypes and frequencies of
ERCC2 gene polymorphism alleles on tumor stage in ovarian cancer patients
.
| | Stage | SI () | SII + SIII () | OR (95% CI) | | | ERCC2-Lys751Gln | Number (%) | Number (%) | OR (95% CI) |
| | Lys/Lys | 7 (3.7%) | 55 (23%) | 1.00 Ref. | | | Lys/Gln | 13 (6.8%) | 51 (21.2%) | 2.00 (0.74–5.42) | 0.254 | | Gln/Gln | 170 (89.5%) | 134 (55.8%) | 9.96 (4.40–22.60) | <0.0001 | | Lys | 27 (7.1%) | 161 (33.5%) | 1.00 Ref. | | | Gln | 353 (92.9%) | 319 (66.5%) | 6.59 (4.27–10.19) | <0.0001 |
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; crude odds ratio (OR); 95% CI: confidence interval at 95%; Chi square.
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