Research Article
CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration
Table 10
Binomial logistic regression analysis of the CYP4F2 (1347C>T; V433M) rs2108622 in the males with eAMD and in the control group by age.
| Model | Genotype | OR (95% CI) | value | AIC |
| <65 | | | | | Codominant | T/T | 1.583 (0.129; 19.422) | 0.719 | 44.539 | T/C | 0.559 (0.091; 3.446) | 0.531 | Dominant | T/C + T/T | 0.713 (0.141; 3.612) | 0.682 | 43.065 | Recessive | T/T | 2.00 (0.177; 22.550) | 0.575 | 42.948 | Overdominant | T/C | 0.518 (0.089; 3.002) | 0.463 | 42.662 | Additive | — | 1.045 (0.298; 3.667) | 0.945 | 43.230 | ≥65 | | | | | Codominant | T/T | 0.062 (0.005; 0.720) | 0.026 | 53.304 | T/C | 0.123 (0.014; 1.108) | 0.062 | Dominant | T/C + T/T | 0.103 (0.012; 0.871) | 0.037 | 51.927 | Recessive | T/T | 0.248 (0.048; 1.276) | 0.095 | 56.239 | Overdominant | T/C | 0.417 (0.105; 1.661) | 0.215 | 57.207 | Additive | — | 3.670 (1.282; 10.502) | 0.015 | 52.149 |
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