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Advances in Materials Science and Engineering
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Advances in Materials Science and Engineering
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2015
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Article
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Tab 3
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Research Article
A 3D Osteoblast
In Vitro
Model for the Evaluation of Biomedical Materials
Table 3
Time of formation and stability of spheroids produced with primary human or murine line cells, at an initial density of 20,000 cells (
).
Cell type
Average time of aggregate formation
Limit of stability on culture
Primary human bone cells
7.1 ± 2.2 days
35 ± 5.5 days
MC3T3-E1
2.0 ± 0.6 days
20.6 ± 5.4 days