Association of Oxidative Stress Markers with Atherogenic Index of Plasma in Adult Sickle Cell Nephropathy

Table 1

Biochemical and lipid profile of sickle cell disease controls, macroalbuminuria, and chronic kidney disease.

Variables	SCD controls	SCD macroalbuminuria	SCD CKD	Reference range
Number of subjects	65	30	15
Age (years)	21.1±6.0	24.5±7.0	31.8±2.0 *
Urea (mmol/L)	2.6±0.9	8.3±2.0^∗	14.2±2.6^∗	1.7–8.3
Creatinine (μmol/L)	57.3±9.8	260±25^∗	498±75^∗	53–116
eGFR (mL/min)	101±2.3	72±5.0^∗	15.1±2.0^∗	90–128
Triglyceride (mmol/L)	1.16±0.4	1.20±0.2	1.7±0.25^∗	<1.7
Total cholesterol (mmol/L)	3.06±0.5	3.45±0.6^∗	3.9±0.34^∗	3.1–6.2
HDL-cholesterol (mmol/L)	0.72±0.2	0.70±0.3	0.06±0.08^∗	0.8–1.9
LDL-cholesterol (mmol/L)	1.90±0.5	1.8±0.32^∗	1.82±0.06^∗	<3.99
VLDL-cholesterol (mmol/L)	0.47±0.06	0.52±0.06^∗	0.74±0.06^∗	<0.8
AIP	0.22	0.23	0.45	<1.44
TC: HDL	4.25	4.92	6.50	<4.9
LDL: HDL	2.67	2.57	3.03	<2.4

eGFR: estimated glomerular filtration rate; AIP: atherogenic index of plasma; *𝑃<0.001.