Elevated Circulating Angiogenic Progenitors and White Blood Cells Are Associated with Hypoxia-Inducible Angiogenic Growth Factors in Children with Sickle Cell Disease

Table 4

Bivariate linear regression showing relationship between Hemoglobin SS group, WBC, and CPC types. WBC was found to be a strongly associated with CPC number in the Hemoglobin SS group. Significant reductions in the beta-coefficient (>25%) compared to the main exposure variable are marked with an asterisk (*).

	Outcome variables
Exposure variables	CD34		CD34/CXCR4		CD34/VEGFR2		CD34/CXCR4/VEGFR2
	β	Adj 𝑟^2	β	Adj 𝑟^2	β	Adj 𝑟^2	β	Adj 𝑟^2
Group = Hb SS	0.94	0.19	1.24	0.28	1.45	0.29	1.06	0.14
Hb SS + WBC	−0.11*	0.36	0.22*	0.39	1.06*	0.29	0.32*	0.17