Review Article
Fanconi Anemia Proteins and Their Interacting Partners: A Molecular Puzzle
Table 1
List of FA protein partners.
| Functional class | Specific function | Protein name | Interacts with | References |
| Transcription | Transcriptional repressor | FAZF | FANCC | [112, 147] | HES1 | FANCA, F, G, L | [44] | Stress-induced chaperone | Hsp70 | FANCC | [112, 140] | GRP94 | FANCC | [60, 112] | Chromatin modifier | BRG1 | FANCA | [112, 154] |
| Cell cycle | Serine/threonine kinase | cdc2 | FANCC | [86, 112] |
| Cell signaling | Cytokine response | STAT1 | FANCC | [133] | IKK2 | FANCA | [79, 82, 112] | Secondary modification | Akt kinase | FANCA | [79, 112] |
| Oxidative metabolism | Electron transfer | RED | FANCC | [112, 114] | Cytosolic Detoxifying enzyme | GSTP1 | FANCC | [112, 113] | Metabolism of xenobiotics | CYP2E1 | FANCG | [112, 115] | Antioxidant enzyme | PRDX3 | FANCG | [68] |
| Transporter | Intracellular trafficking | SNX5 | FANCA | [66, 112] |
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