Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India

Table 2

Hematological parameters in pancytopenia.

	Megaloblastic anemia	Aplastic anemia	Leukemia	Infections	Myelophthisis	Other	All pancytopenia
	Mean ± standard deviation
Hb (g/dL)	5.2±1.6	3.8±1.7	5.7±1.3	6.1±1.3	5.0±1.1	7.4±0.7	5.3±1.6
TLC (×10^9 cells/L)	2.63±0.88	2.16±0.65	2.88±0.91	2.66±0.69	2.58±0.10	3.31±0.35	2.64±0.84
Platelets (×10^9 cells/L)	82±35	47±20	84±14	100±23	70±31	73±19	82±32
ANC (×10^9 cells/L)	1.61±0.82	0.79±0.61	1.23±0.95	1.66±0.78	1.52±0.65	2.22±0.22	1.53±0.83
RDW	16.9±5.6	14.9±2.3	15.0±3.4	14.8±4.8	14.8±2.7	15.0±2.0	16.1±5.0
MCV (fl)	95.1±14.7	90.0±9.7	92.1±7.1	85.9±10.9	90.9±3.3	94.8±2.5	92.8±13.1
MCH (pg)	27.7±2.7	28.9±3.8	27.5±2.5	26.9±2.9	27.3±3.3	24.6±0.9	27.5±2.8
MCHC	33.5±1.6	33.4±2.3	32.6±1.9	33.4±1.2	33.6±0.9	32.6±1.2	33.4±1.6
Retic count (%)	1.9±0.9	0.7±0.2	1.8±0.8	1.5±0.9	2.1±0.8	1.5±0.6	1.7±0.9
Hypersegmented neutrophils	24 (30.4%)	0 (0%)	1 (9.1%)	1 (5%)	1 (25%)	0 (0%)	27 (21.3%)
Macrocytosis	29 (34.1%)	1 (9.0%)	1 (7.6%)	3 (13.04%)	1 (25%)	0 (0%)	35 (25%)
Macroovalocytosis	29 (34.1%)	1 (9.0%)	0 (0%)	2 (8.69%)	0 (0%)	0 (0%)	32 (21.2%)

Hb: hemoglobin; TLC: total leukocyte count; AEC: absolute eosinophil count; ANC: absolute neutrophil count; RDW: red cell distribution width; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; Retic count: reticulocyte count.