Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India

Table 4

Hematological parameters of patients at follow up.

	MA	AA	Leukemia/lymphoma	Infections	Myelophthisis	Other	All Pancyto- penia	𝑃 value^†
	𝑁=55	𝑁=8	𝑁=6	𝑁=12	𝑁=2	𝑁=3	𝑁=86
		Mean ± standard deviation
Hb (g/dL)	12.3±0.9	9.4±2.0	12.8±0.9	12.3±1.3	10.1±4.6	11.1±1.4	12.0±1.5	0.001
TLC (×10^9 cells/l)	7.5±1.9	5.1±2.1	8.2±2.4	7.0± 2.6	6.6± 4.5	6.1± 1.4	7.2± 2.2	0.001
Platelets (×10^9 cells/L)	267±88	255±138	256±78	249±69	180±71	287±142	262±91	0.001
ANC (×10^9 cells/L)	5.5±1.5	3.5±1.5	5.8±1.7	4.8±1.8	4.9±4.1	4.3±1.6	5.2±1.7	0.001
RDW	12.8±1.1	12.2±0.6	13.4±1.2	12.6±1.1	12.8±2.2	13.1±1.7	12.7±1.1	0.132
MCV (fl)	85.9±6.7	86.6±4.7	91.5±4.9	86.1±6.8	92.5±2.4	88.3±4.0	86.6±6.4	0.044
MCHC	33.7±1.7	32.5±1.8	33.2±1.7	34.0±1.3	33.5±1.2	32.8±1.3	33.5±1.6	0.476
MCH (pg)	29.6±2.2	28.7±2.4	29.4±2.5	30.6±3.1	31.2±1.2	28.4±3.8	29.7±2.4	0.001
Retic count corrected	3.2±1.1	1.7±1.5	4.0±1.4	2.6±1.2	2.7±0.7	3.5±0.3	3.1±1.3	0.000

Hb: hemoglobin; TLC: total leukocyte count; AEC: absolute eosinophil count; ANC: absolute neutrophil count; RDW: red cell distribution width; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; Retic count: reticulocyte count; LDH: lactate dehydrogenase.
^†Student’s 𝑡-test for significant difference of means at presentation and on follow up.