Towards a Molecular Understanding of the Fanconi Anemia Core Complex

Table 1

Fanconi Anemia genes and their products.

Gene	MW (kDa)	No. of amino acids	Patient mutations
A	163	1455	60%
B	98	859	2%
C	63	558	13%
D1	384	3418	2%
D2	164	1451	3%
E	59	536	3%
F	42	374	3%
G	68	622	9%
I	150	1328	1%
J	141	1249	2%
L	42	375	0.2%
M	232	2048	0.2%
N	131	1186	0.6%
O	42	376	0.5%
P	200	1834	0.5%
FAAP24	24	215	—
FAAP100	100	881	—
MHF1	16	138	—
MHF2	10	81	—

Amino acids numbers were taken from the NCBI webserver, and patient mutational information was obtained from the Rockerfeller FA Mutations Database and was calculated as a percentage of all individuals recorded in the database.