Thalassemic DNA-Containing Red Blood Cells Are under Oxidative Stress
Figure 2
The frequency of HJ-cells and their oxidative status in normal donors and thalassemic patients. Cells obtained from the blood of normal donors and splenectomized and nonsplenectomized thalassemic patients ( in each group) were stained and analyzed as in legends to Figure 1(a). (a) The frequency of HJ-RBCs. (b) ROS generation. (c) PS exposure. The results are expressed as the percentage in the RBC population (a), the average ± S.D of the mean DCF-fluorescence index (MFI) for ROS (b) and the percentage of cells positively stained with annexin-V for PS (c).
