Research Article

Absolute Reticulocyte Count and Reticulocyte Hemoglobin Content as Predictors of Early Response to Exclusive Oral Iron in Children with Iron Deficiency Anemia

Table 3

Descriptive characteristics of patients, divided into CERs = complete early responders (i.e., normal Hb value at day +30 for therapy onset), PERs = partial early responders (Hb value at day +30 at least 50% higher than the original one), and NERs = not early responders. values come from Wilcoxon sum rank test.
(a)

CERs ()PERs + NERs ()

(%)(%) value

Male14(63.64%)8(36.36%)0.430
Female10(83.33%)2(16.67%)

Mean (SD)Mean (SD) value

T0 Hb (g/dL) 7.00 (1.03) 6.46 (1.60)0.134
T1 Hb (g/dL) 7.67 (1.02) 6.63 (1.68)0.050
T2 Hb (g/dL) 11.33 (1.15) 8.70 (0.94)<0.001

T0 ARC (/mmc)63820(29399)94280(39813)0.040
T1 ARC (/mmc)177077(113504)148200(63023)0.620
T2 ARC (/mmc)63300(33954)107560(32749)0.002
(T1 ARC − T0 ARC)/T0 ARC2.92(4.87)0.58(0.29)0.023

T0 CHr (pg)19.04(2.33)16.73°(1.44)0.020
T1 CHr (pg)22.95(2.38)18.41°(1.69)0.001
T2 CHr (pg)27.66(2.99)20.73°(3.38)0.001
(T1 CHr−T0 CHr)/T0 CHr0.21(0.14)0.11°(0.14)0.042
°

(b)

CERs + PERs ()NERs ()

(%)(%) value

Male18(81.82%)4(18.18%)1.000
Female10(83.33%)2(16.67%)

Mean (SD)Mean (SD) value

T0 Hb (g/dL) 6.78 (1.12)7.13(1.73)0.790
T0 Hb (g/dL) 7.40 (1.20)7.18(1.90)0.750
T0 Hb (g/dL) 11.00 (1.35)8.47(1.14)0.001

T0 ARC (/mmc)71143(35210)80417(36866)0.580
T0 ARC (/mmc)178991(105758)120017(61270)0.120
T0 ARC (/mmc)70354(36863)104150(39149)0.040
(T1 ARC−T0 ARC)/T0 ARC2.60(4.56)0.49(0.23)0.005

T0 CHr (pg)18.56(2.49)17.35°(1.39)0.300
T1 CHr (pg)22.42(2.73)18.07°(0.91)0.001
T2 CHr (pg)27.09(3.30)19.35°(2.60)<0.001
(T1 CHr−T0 CHr)/T0 CHr0.22(0.14)0.04°(0.06)0.006
°