Research Article

Factors Associated with Growth Retardation in Children Suffering from Sickle Cell Anemia: First Report from Central Africa

Table 1

Characteristics of the study population.

ParametersPatients 
()

Age, years
 Mean (SD)
Age distribution, years
 <4 years, (%)(31.6)
 5–9 years, (%)(32.5)
 10–14 years, (%)(25)
 ≥15 years, (%)(10.9)
Gender
 Male, (%)118 (46.1)
 Female, (%)138 (53.9)
Anthropometrics parameters
 Mean weight (kg) (range) (7–62)
 Mean height (cm) (range) (63–172)
 Mean BMI, (10.9–22.9)
Clinical findings
 Hepatomegaly, (%)136 (53.1)
 Splenomegaly, (%)109 (41.7)
Sickle cell crises
 Haemolysis, (%)136 (53.1)
 Severe pain crisis, (%)170 (66.4)
 Hand-foot syndrome, (%)85 (33.2)
 Severe infection, (%)45 (17.6)
 splenic sequestration, (%)19 (7.4)
 Mean age at the first pain crisis (range), months (2–108)
 Mean age at the first transfusion (range), months (2–132)
 Number of severe pain crises/year, (range) (1–20)
 Number of blood transfusions, (range) (0–30)
Laboratory features
 Mean Hb (g/dl) (4.3–11)
 Mean Ht (%) (12.2–35)
 Mean WBCs (103/mm3) (4.6–34.2)
 Mean platelets (103/mm3) (range) (114–582)

, body mass index; Hb, hemoglobin; Ht, hematocrit; WBCs, white blood cells.