Research Article
Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency
Table 4
G6PD levels categorized by the genotype of G6PD mutations and clinical phenotypes of 73 affected males and 27 heterozygous females.
| | Genotype of G6PD mutation | G6PD level categorized by clinical phenotype (IU/ml.RBC) (mean±SD (min–max)) | | Neonatal Jaundice | Acute hemolytic anemia | | Affected male (66) | Heterozygous female (24) | Affected male (7) | Heterozygous female (3) |
| | Viangchan | 16.8 ± 9.6 (5–45) | 125.2 ± 53.7 (61–189) | 8 | 148 | | Canton | 12.3 ± 8.2 (3–26) | 123.7 ± 76 (85–195) | 3 | 84 | | Kaiping | 11.8 ± 11.3 (7–34) | 9, 129, 180 | 12, 25 | - | | Mahidol | 11.75 ± 4.5 (8–17) | 108, 136 | — | 109 | | Quing Yan | 13 | 100, 152, 177 | — | — | | Aures | 10 | — | 3 | — | | Coimbra | 34 | — | 23 | — | | Songklanagarind | 3, 28 | — | — | — | | Union | 10 | — | 9 | — | | Valladolid | 76 | 159 | — | — | | Chinese-5 | 25 | — | — | — | | Mediterranean | 15 | — | — | — | | G6PD level (IU/ml.RBC) (mean±SD (min–max)) | 17.26 ± 11.7 (3–76) | 136.1 ± 44.6 (9–195) | 11.8 ± 8.9 (3–25) | 113.7 ± 32.2 (84–148) |
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Data shown as mean+_SD or number (percent).
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