Associated Factors of Cholelithiasis among Younger Children with Sickle Cell Disease at the National Reference Center for Sickle Cell Disease in Brazzaville, Congo

Table 2

Type of SCD and baseline biological parameters in sickle cell children with and without cholelithiasis and their relationship to cholelithiasis at the National Reference Center for Sickle Cell Disease.

Characteristics	Cholelithiasis		Without cholelithiasis		OR	IC 95%
	n	(%)	n	(%)
Type of SCD
S/β thalassemia	6	16.22	21	28.38	0.57	0.25–1.29	0.16
SS	31	83.78	53	71.62	1.17	0.96–1.43
SC	0	—	0	—
Hb (g/dL)
<6	13	35.14	14	18.92	1.82	0.69–4.74	0.21
≥6	24	64.86	60	81.08	0.8	0.54–1.15
MCV (FL)
<100	24	64.86	44	59.46	0.86	0.80–1.47	0.58
≥100	13	35.14	30	40.54	1.09	0.44–1.62
MCHC (g/dL)
<32	19	51.35	23	31.08	1.26	0.63–2.52	0.81
≥32	18	48.65	51	68.92	0.85	0.53–1.38
WBC (/mm^3)
<12000	21	56.76	44	59.46	0.67	0.39–1.13	0.11
≥12000	16	43.24	30	40.54	1.7	0.85–3.38
Platelets (giga/L)
150–450	31	83.78	56	75.68	1.28	0.89–1.82	0.17
≥450	6	16.22	18	24.32	0.51	0.18–1.41

Sickle beta-zero-thalassemia (5 cases vs 8 controls) and sickle beta-plus-thalassemia (1 case vs 13 controls). Mean corpuscular volume. Mean corpuscular Hb concentration. White blood cells.