Exploring Factors Associated with Quality of Life in Caregivers of Children and Adolescents with Sickle Cell Disease and HIV: A Comparative Analysis
Table 1
Comparing selected variables between caregivers of SCD and HIV at Laquintinie between February and May 2023.
Variables
HIVc (n = 95)
SCDc (n = 104)
Overall sample
value
Patient characteristics
Mean age in years
11.33 (±3.93SD)
8.28 (±4.87SD)
9.73 (±4.69SD)
<0.001
Mean number of hospitalisations in the past 12 months
0.24 (±0.78SD)
1.63 (±1.60SD)
0.97 (±1.45SD)
<0.001
Duration since disease diagnosis
8.42 (±4.13SD)
5.64 (±4.14SD)
6.97 (±4.36SD)
<0.001
Male gender
49 (51.58%)
54 (51.92%)
103 (51.76%)
0.961
Hospitalised in the previous month
—
24 (23.1%)
24 (12.06%)
<0.001
Caregivers’ characteristics
Mean age in years
42.27 (±10.34SD)
38.82 (±9.78SD)
40.47 (±10.18SD)
0.016
Mean number of years living with the patient
10.48 (±4.27SD)
7.92 (±4.84SD)
9.14 (±4.75SSD)
<0.001
Female gender
75 (78.95%)
93 (89.42%)
168 (84.42%)
0.042
Monthly revenue <50, 000 FCFA
40 (42.11%)
39 (37.5%)
79 (39.7%)
0.507
Monthly expenditures on medications <75,000 FCFA
95 (100%)
94 (90.39%)
189 (94.97%)
0.002
Monthly expenditures on hospital bills <75,000 FCFA
93 (97.89%)
8 (7.69%)
101 (50.75%)
<0.001
Anxiety, depression, and QoL metrics
Mean PHQ-9 score
0.56 (±0.88SD)
5.79 (±5.18SD)
3.29 (±4.6SD)
<0.001
Mean GAD-7 score
1.34 (±1.27SD)
5.71 (±4.78SD)
3.63 (±4.17SD)
<0.001
Mean PedsQL FIM score
93.01 (±7.35SD)
64.86 (±9.20SD)
77.82 (±19.93SD)
<0.001
SD = standard deviation. PedsQL FIM = Paediatric Quality of Life Family Impact Module. GAD-7 = 7-item Generalised Anxiety Disorder Scale. PHQ-9: 9-item Patient Health Questionnaire Scale. Bold values represent statistical significance at p < 0.05.
