Exploring Factors Associated with Quality of Life in Caregivers of Children and Adolescents with Sickle Cell Disease and HIV: A Comparative Analysis
Table 3
Univariate and multivariable analysis of factors associated with quality of life in caregivers of SCD and HIV consulted at Laquintinie between February and May 2023.
Variables included in the model
Univariate analysis model
Multivariable analysis model
B
95% confidence interval for B
value
B
95% confidence interval for B
value
Lower bound
Upper bound
Lower bound
Upper bound
Age of the caregiver
0.5
0.23
0.76
<0.001
0.12
-0.04
0.28
0.152
Female caregiver (REF = male gender)
−12.02
−19.58
−4.47
0.002
−1.14
−5.07
2.8
0.568
Number of years living with the patient
0.65
0.07
1.23
0.028
−0.02
−0.65
0.61
0.945
Age of the patient
0.91
0.32
1.5
0.002
−0.21
−0.97
0.54
0.575
Duration since disease diagnosis
0.86
0.22
1.49
0.008
0
−0.51
0.51
0.994
Number of hospitalisations in the previous year
−6.05
−7.79
−4.31
<0.001
−0.27
−1.5
0.96
0.663
Mean PHQ-9 total score
−3.46
−3.83
−3.09
<0.001
−1.52
−2.08
−0.96
<0.001
Mean GAD-7 total score
−3.76
−4.17
−3.34
<0.001
−1.46
−2.09
−0.83
<0.001
Caregivers’ group: SCDc (REF: HIVc)
−27.15
−31.26
−23.05
<0.001
−11.62
−18.46
−4.78
0.001
Hospitalised during the previous month: yes. (REF = no)
−19.89
−28.04
−11.74
<0.001
1.6
−3.29
6.49
0.517
Spending less than 75k on medications (REF: spending 36k or more on medications)
27.39
15.14
39.64
<0.001
12.33
5.73
18.94
<0.001
Spending less than 75k on hospitalisation (REF: spending 75k or more on medications)
25.26
20.92
29.59
<0.001
0.11
−6.39
6.61
0.972
B: unstandardised coefficient. Bold values represent statistically significant variables representing a two-tailed value at <0.05. SCDc = caregivers of patients with sickle cell disease. HIVc: caregivers of patients with HIV.
