TSH Receptor Reduces Hemoglobin S Polymerization and Increases Deformability and Adhesion of Sickle Erythrocytes

Figure 1

TSH promotes inhibition of HbS polymerization. Reading performed every one minute (approximately) for 30 minutes. The rate of polymerization with TSH 1 mIU/L (a), TSH 2 mIU/L (b), TSH 3 mIU/L, and (c) e TSH 5 mIU/L (d). Reading taken at 700 nm absorbance. N = 4. The results expressed as the mean ± SEM, with 95% confidence interval.

(a)

(b)

(c)

(d)