Rett Syndrome: Coming to Terms with Treatment

Table 4

Rett syndrome (clinical issues).

Cognitive impairment
Epilepsy
Breathing Irregularities
Hyperventilation, breathholding, or both
Gastrointestinal dysfunction
Poor chewing and swallowing	Gastroesophageal reflux
Delayed gastric emptying	Constipation
Gallbladder dysfunction
Growth
Sleep
Ambulation
Self-abuse
Quality of Life
Longevity
Other associated features
Hypertonia	Progressive dystonia
Prolonged QTc interval	Bruxism
Vasomotor disturbances