Hyaluronan Does Not Affect Bupivacaine’s Inhibitory Action on Voltage-Gated Potassium Channel Activities in Bovine Articular Chondrocytes
Figure 2
Representative whole cell patch clamp recordings showing outward currents elicited by depolarization at 150 mV with holding for 200 ms. Bovine articular chondrocytes were treated with PBS (a), 7.5 mg/mL hyaluronan (b), 0.25% bupivacaine (c), and a mixture of 7.5 mg/mL hyaluronan and 0.25% bupivacaine (d). (e) Means and standard errors (error bars) of the outward currents recorded in five chondrocytes (). values were obtained by Student’s t-test (two-tailed).
