Vacuum Assisted Closure Therapy versus Standard Wound Therapy for Open Musculoskeletal Injuries

Table 4

Comparison of histological parameters from day 0 to day 8 by Wilcoxon signed ranks test.

Stages of wound healing	Saline wet to moist				VAC
	Positive	Negative	Equal	𝑃 value	Positive	Negative	Equal	𝑃 value
Inflammatory cells	1	10	4	0.001	1	12	2	0.003
Proliferative fibroblasts	13	0	2	0.001	15	0	0	0.001
Collagen formation	14	0	1	0.001	15	0	0	0.001
Fibrosis	6	0	9	0.03	15	0	0	0.001

𝑃 value < 0.05.
Positive: ranks of day 8 > ranks of day 0.
Negative: ranks of day 8 < ranks of day 0.
Equal: ranks of day 8 is equal to ranks of day 0.