A Ratiometric Fluorescence Imaging System for Surgical Guidance
Figure 4
Relative PpIX fluorescence
intensities as a function on position on the CCD image (centered at the 400
pixel value), showing how this varies with the angle between the optical axis
(i.e., laparoscope direction) and the tissue surface, for the different optical
properties: (a) 0°, (b) 15°, (c) 30°. Graphs on the
left are the uncorrected data; those on the right are after applying the double-ratio
algorithm (with linear fits to the combined data). In each plot, the signals
are summed along the axis perpendicular to the x-axis of the graphs on the 3D
CCD array. All measurements were made at 2 cm working distance.