Formulation, Optimization, and Characterization of Repaglinide Loaded Nanocrystal for Diabetes Therapy

Table 2

Independent variables.

Independent variable	Levels
	1	2	3
Polymer	PEG 4000	Poloxamer188	PVA
% Polymer; concentration	0.75%	1.5%	2.25%
Number of cycles	5	8	15
HPH pressure (BAR)	500	1000	1500