Research Article
Formulation, Optimization, and Characterization of Repaglinide Loaded Nanocrystal for Diabetes Therapy
Table 5
Stability study of optimized formulation.
| Stability study | Particle size (nm) | Zeta potential (mV) | (Mean ± SD) | (Mean ± SD) |
| Starting formulation | 187 ± 5.09–29.4 ± 1.00 | | After 3 months | | | 5°C ± 3°C (refrigerator) | 190 ± 2.21–28.1 ± 0.22 | | 30°C ± 2°C/65% ± 5% RH | 195.4 ± 1.89 | −25.5 ± 1.2 | (Ambient conditions) | 40°C ± 2°C/75% ± 5% RH | 201.8 ± 3.1 | −22.2 ± 1.8 | (Stability Chamber) |
|
|