The Cold Contact Method as a Simple Drug Interaction Detection System

<table>(a) The contact area of methampyrone-phenylbutazon
indicated peritecticum mixture: (1) before heating, (2) phenylbutazon melted at 105ºC, (3) contact
area-1 melted at 119ºC, (4) contact area-2 melted at 140ºC, (5) contact area-3
melted at 150ºC, and (6) methampyron melted followed by oxidation at 220–230ºC. (b) DSC
data of phenylbutazon (top), methampyrone (middle), and the mixture of methampyrone-phenybutazon
7 : 3 weight ratio.</table>

Advances in Physical Chemistry

fig2

Figure 2

Figure 2: The Cold Contact Method as a Simple Drug Interaction Detection System 