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Advances in Physical Chemistry
Volume 2011 (2011), Article ID 157484, 11 pages
http://dx.doi.org/10.1155/2011/157484
Research Article

Synthesis, Characterization, and Electrochemical Study of Tetradentate Ruthenium-Schiff Base Complexes: Dioxygen Activation with a Cytochrome P450 Model Using 1- or 2-Methylimidazole as Axial Bases

1Laboratoire d'Électrochimie, d'Ingénierie Moléculaire et de Catalyse Rédox (LEIMCR), Faculté des Sciences de l'Ingénieur, Université Ferhat Abbas, Sétif 19000, Algeria
2SONAS, EA 921, Faculté de Pharmacie, Université d’Angers 16 Boulevard Daviers, 49045 Angers Cedex 01, France

Received 18 September 2010; Revised 21 December 2010; Accepted 22 March 2011

Academic Editor: Milan M. Jaksic

Copyright © 2011 Ali Ourari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Salicylaldehyde, 2-hydroxyacetophenone, and 3,5-dichlorosalicylaldehyde react with 1,2-diaminoethane to give three symmetrical Schiff bases H2L1, H2L2, and H2L3, respectively. With Ru(III) ions, these ligands lead to three complexes: Ru(III)ClL1 ( 𝟏 ), Ru(III)ClL2 ( 𝟐 ), and Ru(III)ClL3 ( πŸ‘ ). The purity of these compounds was estimated by TLC technique and microanalysis while their structures were supported by the usual spectroscopic methods such as NMR, infrared, and electronic spectra. The cyclic voltammetry in acetonitrile showed irreversible waves for all three ligands. Under the same experimental conditions, it was proved that the ruthenium is coordinated in the three complexes 𝟏 , 𝟐 , and πŸ‘ showing quasireversible redox systems. The behavior of these complexes and their comparison with cytochrome P450 are investigated using them as catalysts in the presence of molecular oxygen with an apical nitrogen base: 1- or 2-methylimidazole.