483504.fig.0013a
(a)
483504.fig.0013b
(b)
483504.fig.0013c
(c)
483504.fig.0013d
(d)
Figure 13: The temperature dependence of the free energies. The blue, the black, the red, and the green lines correspond to free energy profiles at 100 K, 200 K, 300 K, and 400 K, respectively.