Full Kinetics and a Mechanistic Investigation of the Green Protocol for Synthesis of β-Aminoketone in the Presence of Saccharose as a Catalyst by a One-Pot Three-Component Reaction

Table 1

Rate constants for the reaction between 1 (10⁻² M), 2 (10⁻² M), and 3 (10⁻² M) in the presence of saccharose as a catalyst and both solvents containing a mixture of methanol and water (methanol/water, 4 : 1) and a mixture of ethanol and water (1 : 1).

Solvent	𝜀	𝑘1×10^2 (min^−1·M^−1)
		𝑇 = 20°C	𝑇 = 25°C	𝑇 = 30°C	𝑇 = 35°C
Methanol : water, 4 : 1	42.08	9.084	16.64	24.18	31.71
Ethanol : water, 1 : 1	52.12	36.85	49.74	62.64	75.53