Organic Compounds Based on (E)-N-Aryl-2-ethene-sulfonamide as Microtubule Targeted Agents in Prostate Cancer: QSAR Study

Table 6

Violations of Lipinski rules.

Compound	MW	HA	HD		Number of violations
1	259.32	2	1	3.332	0
2	293.76	2	1	3.954	0
3	256.22	3	1	4.289	0
4	307.34	4	1	3.396	0
5	319.37	4	1	3.137	0
6	349.4	5	1	3.03	0
7	349.4	5	1	3.03	0
8	379.43	6	1	2.94	0
9	379.43	6	1	2.68	0
10	379.43	6	1	2.94	0
11	365.43	6	2	2.63	0
12	343.32	6	1	3.72	0
13	397.42	7	1	3.1	0
16	394.42	7	2	2.12	0
17	424.42	7	1	2.12	0
18	394.44	7	2	1.86	0
22	412.39	7	1	2.9	0
23	382.41	7	2	2.38	0
24	469.42	8	1	2.08	0
25	409.46	8	3	1.3	0
26	337.37	5	1	3.29	0
27	379.29	9	1	4.2	0
28	424.29	9	1	3.48	0
29	394.32	9	2	3.22	0
30	424.29	9	1	3.48	0
31	394.32	9	2	3.22	0
32	439.23	12	1	4.94	1
33	376.43	5	2	2.6	0
34	390.45	5	2	3.12	0
35	404.48	5	2	3.24	0
36	452.53	5	2	4.16	0
37	470.52	6	2	4.32	0
38	531.42	5	2	4.96	1
39	362.4	5	3	2.29	0
40	376.43	5	3	2.81	0
41	390.45	5	3	2.93	0
42	438.5	5	3	3.85	0
43	456.49	6	3	4.01	0
44	472.94	5	3	4.47	0
45	517.394	5	3	4.64	1