Research Article

Lowering the Risk of Rectal Cancer among Habitual Beer Drinkers by Dietary Means

Table 2

Odds ratios (ORs), 95% confidence intervals (95% CIs) and P values for categories of beer consumption for rectal cancer unadjusted and adjusted for other risk factors. Data from the Melbourne Colorectal Cancer Study.

Upper levelof intake/dayof category (ml/day)Unadjusted(a)Adjusted(b)
OR(c)(95% CI)OR(c)(95% CI)

Beer intake
None1.001.00
Any1.68*** ( 1 . 2 5 , 2 . 2 7 ) 1.75*** ( 1 . 2 8 , 2 . 4 1 )
 1–200 ml/day1.29 ( 0 . 8 4 , 1 . 9 8 ) 1.34 ( 0 . 8 6 , 2 . 0 7 )
 201–740 ml/day1.83** ( 1 . 2 1 , 2 . 7 9 ) 1.99** ( 1 . 2 8 , 3 . 0 8 )
 More than
 740 ml/day
2.15*** ( 1 . 3 8 , 3 . 3 6 ) 2.28*** ( 1 . 4 0 , 3 . 6 9 )
  Trend1.31*** ( 1 . 1 4 , 1 . 5 0 ) 1.34*** ( 1 . 1 6 , 1 . 5 5 )

(a) Adjusted for age and sex only.
(b) Adjusted for age and sex, alcohol (yes/no), body mass index (quintiles), energy intake (quintiles), family history of colorectal cancer (yes/no), oral contraceptive pill use (yes/no), and cigarette pack-years (none, 1–19, 20–39, or ≥40), aspirin (yes/no), and NSAIDS (yes/no).
(c) 𝑃 . 0 1 , 𝑃 . 0 0 1 .