Clinical Study

A Randomized Trial Assessing the Effectiveness of Ezetimibe in South Asian Canadians with Coronary Artery Disease or Diabetes: The INFINITY Study

Table 2

Lipid profile.

ParameterEZE + Statin
STAT2 Value
(Between-Group)


Baseline, mmol/L (mean ± SD)
 Total cholesterol 0.161
 LDL-C 0.140
 HDL-C 0.589
 Triglycerides 0.386
 Total cholesterol/HDL-C ratio 0.376


Six weeks, mmol/L (mean ± SD)
 Total cholesterol 0.351
 LDL-C 0.223
 HDL-C 0.738
 Triglycerides 0.547
 Total cholesterol/HDL-C ratio 0.197


Twelve weeks, mmol/L (mean ± SD)*
 Total cholesterol 0.563
 LDL-C 0.294
 HDL-C 0.351
 Triglycerides 0.287
 Total cholesterol/HDL-C ratio 0.046

LDL-C: low density lipoprotein cholesterol, HDL-C: high density lipoprotein cholesterol.
*12 weeks results account for 2 crossovers in treatment assignment, reflecting treatment actually received (Figure 2).