Table 5: Exploratory Markers*.

ParameterEZE + StatinSTAT2 -Value (Between-Group)**

Baseline

C-reactive Protein (mg/L)Mean ± SD
0.567
Median (Min; Max)1.50 (0.00; 13.00)2.00 (0; 27.00)
Interleukin-6 (pg/mL) Mean ± SD 0.883
Median (Min; Max)3.05 (1.00; 20.00)2.92 (0.00; 9.00)
Apolipoprotein-B (g/L)Mean ± SD 0.543
Median (Min; Max)0.90 (0.57; 1.30)0. 91 (0.61; 1.34)
Apolipoprotein-A1 (g/L)Mean ± SD 0.780
Median (Min; Max)1.43 (1.08; 1.89)1.39 (0.85; 2.10)
ApoB/ApoA1Mean ± SD 0.700
Median (Min; Max)0.62 (0.33; 1.07)0.62 (0.41; 1.00)
Adiponectin (mg/L)Mean ± SD 0.276
Median (Min; Max)6.96 (3.89; 24.90) 7.82 (4.20; 16.59)
Leptin (ng/mL)Mean ± SD26.96 ± 30.1618.48 ± 13.140.623
Median (Min; Max)17. 90 (2.00; 1.42)13.97 (3.00; 46.00)

12 weeks mmol/L

C-reactive Protein (mg/L)Mean ± SD 0.079
Median (Min; Max)1.10 (0.00; 16.00)1.90 (0.00; 17.00)
Interleukin-6 (pg/mL) Mean ± SD 0.306
Median (Min; Max)3.08 (1.00; 5.00)3.11 (1.00; 24.00)
Apolipoprotein-B (g/L)Mean ± SD 0.110
Median (Min; Max)0.67 (0.44; 1.41)0.79 (0.55; 1.06)
Apolipoprotein-A1 (g/L)Mean ± SD 0.754
Median (Min; Max)1.40 (1.07; 1.66)1.42 (0.82; 1.98)
ApoB/ApoA1Mean ± SD 0.252
Median (Min; Max)0.50 (0.30; 1.04)0.55 (0.38; 1.05)
Adiponectin (mg/L)Mean ± SD 0.638
Median (Min; Max)7.35 (3.48; 17.42)7.36 (3.99; 14.76)
Leptin (ng/mL)Mean ± SD 0.832
Median (Min; Max)19.10 (3.00; 206.00)21.40 (2.00; 65.00)

*Analysis performed on those patients with available data
**Mann-Whitney U non-parametric test for independent samples or independent samples t-test, depending on distribution assessed with Shapiro-Wilk test of normality.
For parameters not normally distributed, the median rather than the mean should be preferred.