Table 1: Rationale for the ingredients included in After-Effect©.

IngredientsDose1EffectImproved symptoms2Reference

Borago seeds oil (22% GLA)1500 mgPrecursor of prostaglandin1Headache, laziness, being tired[18]
Magnesium56.25 mgMight be deficientWithdrawal symptoms[19, 20]
Headaches[21]
B6 vitamin2 mgRole in immune systemUncomfortable feeling[22]
B1 vitamin4.2 mgMight be deficientImpatience, restlessness[22, 23]
C vitamin120 mgAntioxidative properties[24]
Fish oil (18% EPA, 12% DHA)157.5 mgAnti-IL1 effect[25]
Pro-inflammatory cytokines[26]
Silybum marianum
(2% silymarin)
80 mgHepatoprotective properties[2729]
Opuntia ficus indica
(polar extract)
60 mgAnti-oxidative properties[24]

1Total dose of 5 capsules. 2Only those symptoms that showed a significant improvement during alcohol hangover are listed. GLA: gamma-linolenic acid, EPA: eicosapentaenoic acid (EPA), and DHA: docosahexaenoic acid.