Characterization of Prejunctional Muscarinic Receptors: Effects on the Release of VIP and Functional Responses and Receptor Expression in the Ovine Submandibular Gland
Figure 1
Comparison of the changes in submandibular flow of saliva (A), submandibular protein output (B), submandibular vascular resistance (C), and VIP output (D) in response to chorda tympani stimulation at 8 Hz continuously for 10 minutes (from point of time 0 to 10; indicated by horizontal bar) in the absence (▲) and in the presence (■) of methoctramine (left column of panels; 100 g kg−1 IV) in 5 anesthetized sheep and in the absence (▲) and in the presence (■) of pirenzepine (right column of panels; 40 g/kg iv) in 6 anesthetized sheep. Values are means ± S.E.M.
