Research Article
Testosterone and Cholesterol Vasodilation of Rat Aorta Involves L-Type Calcium Channel Inhibition
Table 1
IC50 values (M) of testosterone relaxant effect on rat aortic rings contracted with BAY and with KCl (60 mM) alone or in the presence of the following drugs: the channel blocker 4-aminopyridine (4-AP; 2 mM), the channel blocker tetraethylammonium (TEA; 1 mM), the channel blocker glibenclamide (GLI; 10 M) and the testosterone receptor antagonists flutamide (10 M). Each value represents the mean ± SEM from the number of experiments shown in brackets. * versus testosterone IC50 obtained in KCl-contracted arteries, Student's t-test.
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