A Comparison of the 𝜶2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain

Figure 3

The effects of (a) L-838,417 and (b) TPA023 on tibial nerve transection-induced static allodynia in the rat. Data are means±sem. 𝑛=22. Data are expressed as 50% paw withdrawal threshold (PWT). BL: baseline. (∗∗=𝑃<0.01, ANOVA compared to vehicle-treated group).

(a)

(b)