Research Article

A Comparison of the 𝜶 2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain

Figure 4

The effects of (a) L-838,417and (b) TPA023 on chronic constriction injury-induced static allodynia in the rat. Data are m e a n s ± s e m . 𝑛 = 6 . Data are expressed as 50% paw withdrawal threshold (PWT). BL: baseline. ( = 𝑃 < 0 . 0 5 , ANOVA compared to vehicle-treated group).
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(a)
608912.fig.004b
(b)