Testosterone Increases: Sodium Reabsorption, Blood Pressure, and Renal Pathology in Female Spontaneously Hypertensive Rats on a High Sodium Diet

Table 1

Glomerular scores by treatment and severity.

Group	0	I-II	III-IV
Control (𝑛=8)	1.9 ± 0.6	96.4 ± 0.8	1.7 ± 0.2
OVX (𝑛=6)	0.6 ± 0.08	96.4 ± 0.9	3.0 ± 1.0
Testosterone (𝑛=6)	1.0 ± 0.4	89.3* ± 2.1	9.7* ± 2.4
OVX +T (𝑛=7)	1.4 ± 1.0	83.0** ± 2.8	15.6** ± 3.4

(means, ± S.E.M., *𝑃<.05, **𝑃<.01 compared to controls, OVX: ovarectomy, OVX+T: ovarectomy and testosterone treatment, 0: normal glomerulus, I-II: moderate glomerulosclerosis, III-IV: severe glomerulosclerosis).