(a)

(b)

(c)

Figure 3: ΔSmooth-ΔSPV relative effect profile of SL65.1498 25 mg, zolpidem 10 mg, and alprazolam 1 mg versus lorazepam 2 mg, respectively. (Blue open square: investigational compound; red closed circle: lorazepam 2 mg; blue dot line: the comparator drug, red dash line; lorazepam 2 mg.)