Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways
Table 1
TaqMan Assay IDs (Applied Biosystems, Foster City, USA) of specific proteins and representatives of signal pathways expressed in normal human fibroblasts (NHDFs) and normal human keratinocytes (NHEKs) investigated by real-time PCR after treatment with 10 μg/mL St. John’s Wort herb polysaccharide fractions.
Gene
Function
TaqMan Assay ID
Epidermal growth factor receptor (EGFR)
Proliferation
Hs01076068m1
Fibroblast growth factor 7 (FGF7)
Proliferation
Hs00384281_m1
Insulin receptor (InsR)
Survival/proliferation
Hs00169631m1
Involucrin (Inv)
Differentiation-specific protein
Hs00846307s1
Signal transducer and activator of transcription 6 (STAT6)
