Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways

Table 4

Gene expression of NHEK after 6 h of incubation with 10 μg/mL St. John’s Wort polysaccharides in serum-starved media. Results of RT-PCR with TaqMan Assays were normalized to endogenous control 18srRNA and to respective target gene expression of untreated control cells. Regulation was defined as significant with >2 (+) and <0.5 (−). No change in gene expression is shown as “o”.

	Involucrin	PLA2	EGFR	InsR
Hp1	o	−	−	−
Hp2	o	o	o	o
Hp3	o	o	o	o
Hp4	o	+	o	o