Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica)

Figure 3

Chemical structures of analogues of 6-MSITC. 4-MSITC (sulforaphane), 2-MSITC, and 8-MSITC are analogues of 6-MSITC containing the different length of alkyl chain. 1-(Methylsulfinyl)-6-thiocyanatohexane substituted ITC group in 6-MSITC with thiocyanate group. 6-Isothiocyanatohexanal, 1-isothiocyanato-6-(methylthio)hexane, and n-hexyl ITC substituted the methylsulfinyl group in 6-MSITC with formyl group, methylsulfinyl group, and methyl group, respectively.