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Advances in Pharmacological Sciences
Volume 2012 (2012), Article ID 789713, 4 pages
http://dx.doi.org/10.1155/2012/789713
Research Article

Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook)

1Tapi Valley Education Society, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, India
2Department of Pharmacognosy, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, Maharashtra, India
3Department of Biotechnology, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, Maharashtra, India

Received 24 August 2011; Accepted 8 September 2011

Academic Editor: Lutfun Nahar

Copyright © 2012 Vaishali D. Shewale et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The present work was to evaluate the anti-inflammatory activity of Delonix regia leaves (Family: Caesalpiniaceae). The powder of Delonix regia leaves was subjected to extraction with ethanol in soxhlet extractor. The ethanol extract after preliminary phytochemical investigation showed the presence of sterols, triterpenoids, phenolic compounds and flavonoids. The anti-inflammatory activity was studied using carrageenan-induced rat paw edema and cotton pellet granuloma at a three different doses (100, 200, and 400 mg/kg b.w. p.o.) of ethanol extract. The ethanol extract of Delonix regia leaves was exhibited significant anti-inflammatory activity at the dose of 400 mg/kg in both models when compared with control group. Indomethacin (10 mg/kg b.w. p.o) was also shown significant anti-inflammatory activity in both models.