Table 1: Effect of essential oil of Melissa  officinalis L. on carrageenan-induced rat paw edema.

Treatment groupsDose mg/kg p.o.Mean volume of edema (left paw-right paw) induced by carrageenan (mL)
1 h 30 min3 h6 h

Control
Indomethacin10
EOMO200
EOMO400

Values are expressed as mean ± S.E.M. ( ), p.o.: oral route, : number of animals per group, EOMO: essential oil of Melissa  officinalis  L., statistically significant relative to the control and reference drug (Indomethacin).