Table 2: Percentage of inhibition of inflammation of essential oil of Melissa  officinalis L. using carrageenan-induced rat paw edema.

Treatment groupsDose mg/kg p.o. Percentage of inhibition of inflammation induced by carrageenan (%)
1 h 30 min3 h6 h

Indomethacin1076.4773.0752.94
EOMO20070.5861.5361.76
EOMO40076.7465.3870.58

; these results compared with standard drug (Indomethacin, 10 mg/kg, p.o.) were administered by the oral route.