Table 4: Percentage of inhibition of inflammation of essential oil of Melissa  officinalis L. using experimental trauma-induced rat paw edema.

Treatment groupsDose mg/kg p.o. Percentage of inhibition of inflammation induced by experimental trauma (%)
1 h 30 min3 h6 h

Indomethacin1065.8186.3691.66
EOMO20044.4477.2791.66
EOMO40055.5581.8194.44

; these results compared with standard drug (Indomethacin, 10 mg/kg, p.o.) were administered by the oral route.